Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.


Pronunciation: aw RAN oh fin

Brand: Ridaura


slide 1 of 1, Ridaura,

3 mg, capsule, brown/peach, imprinted with RIDAURA

Image of Ridaura
slide 1 of 1

What is the most important information I should know about auranofin?

You should not use auranofin if you have ever had a severe reaction to gold therapy that affected your skin, lungs, bone marrow, blood cells, or your stomach or intestines.

Auranofin contains gold, which may be toxic and can cause symptoms such as rash, itching, mouth sores, or blood in your urine, or severe diarrhea.

Call your doctor at once if you have a severe skin rash or itching, mouth sores, severe diarrhea, pale skin, unusual tiredness, easy bruising or bleeding, blood in your urine or stools, or if you cough up blood.

What is auranofin?

Auranofin is a form of gold that reduces some of the effects of the inflammatory process in the body.

Auranofin is used to treat rheumatoid arthritis (RA) in adults.

Auranofin is usually given only to people unable to use other RA medications, or when other treatments did not work or have stopped working.

Auranofin will not reverse any cartilage or joint damage that has already occurred in your body.

Auranofin may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking auranofin?

You should not use auranofin if you are allergic to it, or if you have ever had medical problems caused by using gold therapy, such as:

  • an allergic skin reaction;
  • stomach or intestinal problems;
  • a breathing disorder;
  • a bone marrow disorder; or
  • a severe blood cell disorder.

Tell your doctor if you have ever had:

  • a bone marrow disorder or weak immune system;
  • kidney disease;
  • liver disease; or
  • inflammatory bowel disease.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using auranofin.

Auranofin is not approved for use by anyone younger than 18 years old.

How should I take auranofin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take this medicine with a full glass of water.

It may take up to 6 months of using this medicine before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 3 or 4 months of treatment.

Auranofin can increase your risk of bleeding or infection. You will need frequent medical tests.

Your liver and kidney function may also need to be checked.

Store auranofin at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking auranofin?

Auranofin could make your skin more sensitive to sunlight and you may develop a rash or itching. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of auranofin?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pale skin, easy bruising, unusual bleeding (nosebleeds, bleeding gums), purple or red spots under your skin;
  • unusual tiredness, feeling short of breath;
  • severe skin rash or itching;
  • sudden chest pain, wheezing, dry cough, feeling short of breath;
  • severe or ongoing diarrhea, nausea, vomiting, or loss of appetite;
  • black, bloody, or tarry stools; or
  • kidney problems --puffy eyes, swelling in your ankles or feet, blood in your urine, urine that looks foamy.

Auranofin may cause more side effects on the stomach than gold injections cause. If you were switched from gold injections to auranofin capsules, tell your doctor if you have concerns about these side effects. You may need to use auranofin for a few months before your symptoms improve.

Common side effects may include:

  • diarrhea, loose stools;
  • rash, itching; or
  • blisters or ulcers in your mouth, red or swollen gums, trouble swallowing.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect auranofin?

Tell your doctor about all your other medicines, especially:

  • gold injections;
  • hydroxychloroquine;
  • penicillamine;
  • phenytoin;
  • high doses of steroid medication (prednisone and others); or
  • drugs that weaken your immune system, such as azathioprine, cyclophosphamide, methotrexate, and others.

This list is not complete. Other drugs may affect auranofin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about auranofin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 5.01. Revision date: 11/17/2020.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.